BackgroundA positive association between Staphylococcus aureus (S. aureus) colonization and atopic dermatitis (AD) severity has been reported. However, the strength and consistency of this relationship remain unclear.MethodsWe systematically searched P…
IntroductionNeurological involvement in Wiskott–Aldrich syndrome (WAS) – an inborn error of immunity caused by mutations in the WAS gene – is primarily documented through isolated case reports, limiting systematic synthesis and clear characterization o…
ObjectiveThis systematic review and meta-analysis aims to evaluate the effects of Tai Chi Chuan on the expression of pro-inflammatory genes IL-6, IL-1β, and TNF-α—downstream of the NF-κB pathway—in adults with chronic diseases. It further explores pote…
BackgroundAnkylosing spondylitis (AS) is an autoimmune disease. Its exact cause remains unclear. It is generally believed to result from a combination of genetic and environmental factors, as well as immune disorders. However, growing evidence suggests…
BackgroundThe prevalence of female sexual dysfunction (FSD) among women with systemic lupus erythematosus (SLE) is inconsistent, and whether SLE is a risk factor for FSD among women remains controversial. Therefore, this study aimed to conduct a system…
ObjectiveTo compare the efficacy and safety of biologics and targeted small molecule drugs plus stable background therapy for the systemic lupus erythematosus (SLE).MethodsA systematic search was conducted across PubMed, EMBASE and Cochrane Library for…
The clinical management of autoimmune liver diseases is frequently complicated by the concomitant presentation of hepatitic and cholestatic features, an entity clinically designated as Overlap Syndrome. While the majority of patients respond to convent…
ObjectiveThe present Bayesian network meta-analysis (NMA) aims to evaluate and compare the efficacy of aerobic training (AT), resistance training (RT), high-intensity interval training (HIIT), and combined training (CT) on biomarkers of chronic low-gra…
ObjectiveExcessive secretion of inflammatory biomarkers exerts adverse effects on muscle strength and function, and is associated with the development and progression of sarcopenia and frailty. For the improvement of inflammatory biomarker concentratio…
BackgroundTeclistamab, a B-cell maturation antigen (BCMA) × CD3 bispecific antibody (BsAb), has shown remarkable efficacy in relapsed/refractory multiple myeloma (RRMM). However, its mechanism leads to profound hypogammaglobulinemia, making infection a…
