Neuronal TLR9 signalling crucial for memory formation
Nature Reviews Immunology, Published online: 17 April 2024; doi:10.1038/s41577-024-01034-4Neuronal TLR9 signalling crucial for memory formation
NatureReviewsImmunology
Rejuvenating an old immune system
Nature Reviews Immunology, Published online: 09 April 2024; doi:10.1038/s41577-024-01031-7Depletion of myeloid-biased haematopoietic stem cells can mitigate age-associated immune dysfunction.
Generating prophylactic immunity against arboviruses in vertebrates and invertebrates
Nature Reviews Immunology, Published online: 03 April 2024; doi:10.1038/s41577-024-01016-6In this Review, the authors discuss recent advances, current challenges and future prospects in exploiting both vertebrate and invertebrate immun…
Short-chain fatty acids: linking diet, the microbiome and immunity
Nature Reviews Immunology, Published online: 02 April 2024; doi:10.1038/s41577-024-01014-8Short-chain fatty acids (SCFAs) are microbial metabolites that regulate mucosal barrier integrity and immune cell functions. This Review summariz…
PANINI: Combined protein and nucleic acid imaging in tissues
Nature Reviews Immunology, Published online: 28 March 2024; doi:10.1038/s41577-024-01028-2Sizun Jiang (while in the Garry Nolan lab) describes a method termed PANINI that allows simultaneous detection of nucleic acids at low copy numbe…
A pre-TCRα-independent pathway of αβ T cell differentiation
Nature Reviews Immunology, Published online: 19 March 2024; doi:10.1038/s41577-024-01024-6A study in Science reports 10 individuals with pre-TCRα deficiency who have late-onset or no clinical phenotype, which suggests that αβ T cells c…
Bone marrow inflammation in haematological malignancies
Nature Reviews Immunology, Published online: 15 March 2024; doi:10.1038/s41577-024-01003-xHaematological malignancies are associated with inflammation in the bone marrow. In this Review, the authors discuss how tumour-associated inflam…
Strategies for targeting cytokines in inflammatory bowel disease
Nature Reviews Immunology, Published online: 14 March 2024; doi:10.1038/s41577-024-01008-6This Review explains how cytokines contribute to the pathogenesis of inflammatory bowel disease (IBD). The author highlights the cytokine-targeti…
Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation
Nature Reviews Immunology, Published online: 13 March 2024; doi:10.1038/s41577-024-01023-7Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation
Breaking tolerance: the autoimmune aspect of atherosclerosis
Nature Reviews Immunology, Published online: 12 March 2024; doi:10.1038/s41577-024-01010-yIn this Perspective article, Ley and colleagues explain the association between atherosclerosis and the loss of tolerance to self-proteins. They …