Filomena Napolitano

The antimicrobial potential of the secretome from Wharton’s jelly mesenchymal stem cells in the context of regenerative medicine: an in vitro study

5 de May de 2026 by Filomena Napolitano

IntroductionThe secretome derived from Mesenchymal Stem Cells (MSCs) have received significant attention as a promising tool in regenerative medicine. This “cell-free” strategy offers a promising alternative to stem cell therapies, potentially avoiding…

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations

2 de December de 2025 by Filomena Napolitano

IntroductionIn systemic sclerosis (SSc), the laboratory panel lacks biomarkers able to predict the disease course and/or reflect the fibrotic activity in the skin and internal organs. We assessed the association of the serum levels of urokinase (urokin…

The N-formyl peptide receptors: much more than chemoattractant receptors. Relevance in health and disease

4 de March de 2025 by Filomena Napolitano

Pattern Recognition Receptors (PRRs) are a superfamily of receptors that detect molecular structures typical for pathogens and damaged cells and play a crucial role in the proper function of the innate immune system. A particular subgroup of membrane-b…