TREM2 as a central immunometabolic hub in Alzheimer’s disease: linking microglial states, lipid stress, and disease-stage-specific intervention
Triggering receptor expressed on myeloid cells 2 (TREM2) plays a crucial role in regulating microglial function in Alzheimer’s disease (AD) and other neurodegenerative disorders. Genetic studies have identified rare coding variants in TREM2 as signific…