Regulation of macrophage polarization in chronic airway inflammatory diseases: immune interactions, metabolic reprogramming, and beyond

Chronic upper and lower airway inflammatory diseases (such as allergic rhinitis, chronic rhinosinusitis, and bronchial asthma) are a group of highly heterogeneous disorders primarily characterized by immune imbalance and persistent inflammation as thei…

Longitudinal plasma proteomics identifies diagnostic and response-associated inflammatory and immune biomarkers in psoriasis following secukinumab therapy

IntroductionPsoriasis (PSO) is a chronic immune-mediated inflammatory skin disease characterized by keratinocyte hyperproliferation and dysregulated activation of the IL-23/IL-17 axis, leading to persistent cutaneous inflammation and substantial diseas…

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