Hui Wang – InmunoES

NAFLD-associated immune remodeling in colorectal cancer liver metastasis: mechanisms and implications for immunotherapy

29 de June de 2026 by Hui Wang

Non-alcoholic fatty liver disease (NAFLD) affects over 30% of the global adult population and has been increasingly recognized as an adverse prognostic factor for colorectal cancer (CRC) liver metastasis (CRLM). However, the underlying immune mechanism…

Exploratory characterization of IgG1/IgG4 glycosylation and monocyte-derived dendritic cell responses in esophageal squamous cell carcinoma

18 de June de 2026 by Hui Wang

IntroductionIn previous studies, we identified the unique tumor immunosuppressive function of IgG4. This study aims to further characterize the structure of IgG4 and evaluate its potential effects on monocyte-derived dendritic cells (moDCs).MethodsThe …

Mechanistic study on the reduction of TNF-α and β-CTX levels in RA patients by moxibustion combined with western medication through regulation of the Wnt/β-catenin pathway

22 de May de 2026 by Hui Wang

Background and aimsThe pathological core of rheumatoid arthritis (RA) is progressive bone destruction driven by chronic inflammation. The Wnt/β-catenin signaling pathway plays a key regulatory role in bone metabolism, but it is disrupted by the inflamm…

IgG4-mediated M2 macrophage polarization in tertiary lymphoid structures of esophageal cancer: implications for immunosuppression

17 de January de 2025 by Hui Wang

BackgroundOur previous research highlighted the potential role of immunoglobulin G4 (IgG4) in mediating immunosuppression within the tumor microenvironment (TME). Tertiary lymphoid structures (TLS) in the TME have important immune-related functions. Th…