Jing Liu Influenza vaccine effectiveness exhibits significant heterogeneity across age groups, largely shaped by lifelong immune remodeling. This review adopts a continuous spectrum perspective-spanning immune development, immune maturation, and immunosenescenc…
Cellular & Molecular Immunology, Published online: 20 May 2026; doi:10.1038/s41423-026-01425-8PARK7-induced delactylation of ATAD3A impairs mitochondrial fitness to promote exhaustion of tumor-infiltrating CD8+ T cells
This review provides a systematic and critical examination of the multifaceted roles of the CX3CL1/CX3CR1 axis in liver diseases. We emphasize its context-dependent duality—exhibiting both pro- and anti-inflammatory, pro- and anti-fibrotic, and pro- an…
Cellular & Molecular Immunology, Published online: 17 April 2024; doi:10.1038/s41423-024-01149-7Targeting macrophage metabolism to enhance tumor immunotherapy
