Kun Zhang Osteoarthritis (OA) is a degenerative joint disease characterized by synovial inflammation, cartilage degradation, and subchondral bone remodeling. Synovial macrophages, particularly their polarization into pro-inflammatory M1 or anti-inflammatory M2 p…
Ubiquitination is a modification prevalent in eukaryotic cells. Disruptions in ubiquitination processes can have detrimental effects, potentially leading to diseases that endanger life. E3 ubiquitin ligases specifically recognize substrate proteins dur…
BackgroundProstate adenocarcinoma (PRAD) is a leading cause of male mortality, with NK/T cell communication being key areas of the research.MethodsThe Seurat package was utilized to normalize and reduce the dimensionality of the single-cell data, and C…
