Prognostic integration of tumor microenvironment and parthanatos-related genes in gastric cancer: a machine learning-driven risk model and immune landscape profiling

BackgroundThe tumor microenvironment (TME) plays a pivotal role in the progression of gastric cancer (GC) and its response to treatment, particularly by modulating parthanatos (PA). However, the prognostic significance of TME and PA, as well as their p…

The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

BackgroundCirculating tumor DNA (ctDNA) is an emerging biomarker in malignant melanoma(MM), and high levels of ctDNA may reflect a higher tumor load. However, its prognostic value for MM receiving immune checkpoint inhibitors(ICI) remains controversial…

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