Qi Zhang Cellular & Molecular Immunology, Published online: 13 August 2026; doi:10.1038/s41423-026-01457-0MARCH2/3 target FcγRI for K27-linked polyubiquitination and degradation to restrict the inflammatory response
AimTo evaluate the efficacy and safety of transarterial chemoembolization combined with donafenib and camrelizumab (TACE+D+C) versus TACE plus donafenib (TACE+D) in the treatment of hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT)….
Cellular & Molecular Immunology, Published online: 15 August 2025; doi:10.1038/s41423-025-01334-2The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target TIM-1 to limit Zika virus infection
Regulatory B cells (Bregs) are pivotal modulators of immune tolerance, suppressing inflammation through cytokine secretion and cellular interactions. Their role is particularly significant in inflammatory diseases such as type 1 and type 2 diabetes mel…
IntroductionSynbiotics have revealed the possibility of improving constipation through gut microbiota. The synergistic efficacy of Bifidobacterium animalis subsp. lactis BL-99 (BL-99) and fructooligosaccharide (FOS) on constipation have not been invest…
Depression, projected to be the predominant contributor to the global disease burden, is a complex condition with diverse symptoms including mood disturbances and cognitive impairments. Traditional treatments such as medication and psychotherapy often …
