Tao Wang BackgroundThe simultaneous occurrence of severe atopic dermatitis (AD), vitiligo, and alopecia areata (AA) in a single patient is exceptionally rare and poses a significant therapeutic challenge, as conventional “disease-specific” therapies often yield…
Cellular & Molecular Immunology, Published online: 17 March 2026; doi:10.1038/s41423-026-01397-9The type-I interferon priming signal balances antibacterial and antitumor trained immunity in alveolar macrophages
The mechanism that lung epithelial cells regulate immune responses during chronic injury still remains unclear. Here, we combined single-cell RNA sequencing with spatial transcriptomics to track epithelial dynamics in silica (SiO2)-exposed mouse lungs….
AimFunctional cure strategies based on interferon therapy for chronic hepatitis B (CHB) are gaining increasing attention among clinicians. However, studies investigating the duration of response after achieving HBsAg clearance with interferon treatment…
