Data-driven serum cytokine and chemokine phenotypes are associated with MRI-defined disc regression and persistent radicular pain in lumbar disc herniation

BackgroundInflammation after lumbar disc herniation (LDH) may contribute to radicular pain while also participating in resorption of herniated disc material. Whether circulating immune profiles are associated with these endpoint-specific recovery patte…

From static pathology to dynamic immunity: immunological plasticity and histopathological remodeling in atopic dermatitis and psoriasis

Atopic dermatitis (AD) and psoriasis are the two canonical chronic inflammatory skin disorders, classically differentiated by their distinct histopathological features and immune polarization—Th2-dominant in AD versus IL-23/Th17-dominant in psoriasis. …

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