Yang Wang Silybin, as the main active component of milk thistle, has attracted significant attention in recent medical research due to its remarkable anti-inflammatory effect. Inflammatory responses are an important mechanism in the pathogenesis of various clini…
ObjectiveTo evaluate the prognostic significance of the modified Naples Prognostic Score (mNPS) in patients with locally advanced non-small cell lung cancer (NSCLC) after neoadjuvant chemotherapy and surgery.MethodsWe conducted 126 patients with locall…
BackgroundImmune checkpoint blockade (ICB) therapies that inhibit PD-1/PD-L1 signaling have revolutionized oncology, yet their benefits are constrained by limited penetration into tumor tissues, inability to eliminate intracellular PD-L1, and the emerg…
Cellular & Molecular Immunology, Published online: 17 September 2025; doi:10.1038/s41423-025-01343-1Infiltrating macrophages replace Kupffer cells and play diverse roles in severe alcohol-associated hepatitis
