Case Report: Gitelman syndrome with a suspected MEFV- associated autoinflammatory phenotype: diagnostic challenges in a complex case

We report a rare case of genetically confirmed Gitelman syndrome (GS) in a Chinese female patient presenting with systemic inflammatory manifestations and a heterozygous MEFV variant of uncertain significance. The patient initially exhibited arthritis,…

Peripheral blood markers predict prognosis and irAEs of stage IV driver gene-negative lung adenocarcinoma treated with ICIs

ObjectiveThis study aims to evaluate the prognostic significance of peripheral blood biomarkers in relation to outcomes and immune-related adverse events (irAEs) among patients with stage IV driver gene-negative lung adenocarcinoma receiving treatment …

The association of systemic immune-inflammation index with incident breast cancer and all-cause mortality: evidence from a large population-based study

BackgroundChronic low-grade inflammation is recognized as a significant factor in various health outcomes, including the development and progression of breast cancer. The Systemic Immune-Inflammation Index (SII), a novel marker derived from routine blo…

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