Donor-recipient age difference, not donor age alone, predicts outcomes in allogeneic hematopoietic stem cell transplantation for aplastic anemia

BackgroundThe impact of donor age on outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia (AA) remains poorly defined. The prognostic value of donor–recipient age difference (DRAD) has rarely been explored.O…

Gastrointestinal acute graft versus host disease: a translational perspective from pathogenesis to precision prevention and treatment

Allo-HSCT represents a curative option for various hematological disorders. However, aGVHD remains the leading cause of non-relapse mortality following transplantation. The gastrointestinal tract is the most severely affected and prognostically unfavor…

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