Rapidly progressive IgA nephropathy (IgAN) and IgA vasculitis nephritis (IgAVN) are characterized by marked glomerular inflammation, extensive extracapillary proliferation, and rapid renal function decline. Despite increasing insights into their shared…
Psoriasis is an immune-mediated inflammatory skin disorder associated with systemic complications, including an elevated risk of chronic kidney disease (CKD) and progression to end-stage renal disease (ESRD). Managing psoriasis in patients undergoing p…
While dupilumab is highly effective in managing moderate-to-severe atopic dermatitis (AD) through targeted IL-4/IL-13 receptor antagonism, its broader immunomodulatory effects warrant careful clinical scrutiny. We report the case of a 63-year-old male …
BackgroundEosinophilic granulomatosis with polyangiitis (EGPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis characterized by asthma, eosinophilia and inflammation of small-tomedium vessels. Although respiratory and n…
While spice allergies are rarely documented in children, spices are becoming an increasingly common allergen in pre-packaged foods. Current literature reports contradictory findings regarding the risk of severe reactions in pediatric patients, with som…
BackgroundPediatric overlap of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and anti-N-methyl-D-aspartate receptor encephalitis (MNOS) is uncommon. At onset, such cases may resemble infectious or vascular disorders, leading t…
BackgroundAllogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only potentially curative therapy in patients with high-risk myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). However, a considerable proportion of …
Metastatic uveal melanoma (mUM) is a rare, aggressive malignancy with limited therapeutic options in the metastatic setting. Tebentafusp (IMCgp100) is an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC), targeting gp100 in HLA-A*020…
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotizing vasculitis characterized by eosinophilic infiltration and granuloma formation, affecting multiple organs. Gastrointestinal (GI) involvement is relatively uncommon and it typ…
We report the case of a young woman with primary ciliary dyskinesia (PCD) who was also diagnosed with tRNA nucleotidyl transferase 1 (TRNT1)-related autoinflammatory syndrome, characterized by recurrent episodes of fever and arthralgia beginning at age…
