PurposeTo report a rare case of overlapping features of Behçet’s uveitis and multizonal outer retinopathy and retinal pigment epitheliopathy (MORR), documented by longitudinal multimodal imaging.MethodsA single case report.ResultsA 37-year-old male pre…
Generalized pustular psoriasis (GPP) is a severe, relapsing skin disorder characterized by widespread erythema and sterile pustules. Classical systemic therapies often yield suboptimal results. Xeligekimab is a novel, fully human anti-interleukin-17A (…
Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) affecting multiple organs. Distal renal tubular acidosis (dRTA) as a renal irAE is exceedingly rare, often delaying diagnosis due to nonspecific symptoms. A 63-year-old…
We report the case of an 18-year-old previously healthy female who developed acute liver and kidney injuries with cytopenia and hyperinflammatory markers following cytomegalovirus (CMV) infection. Despite not meeting the hemophagocytic lymphohistiocyto…
This study reports three cases of refractory anti-NMDAR encephalitis patients who exhibited persistent severe neuropsychiatric symptoms after first-line immunotherapy (glucocorticoids, intravenous Immunoglobulin) and long-term (maintenance) immunothera…
Acrodermatitis continua of Hallopeau (ACH) is a refractory, chronic, sterile pustular psoriasis predominantly involving the acral regions. Although biologic agents targeting the interleukin-17 (IL-17) pathway have demonstrated clinical promise, systemi…
Patients treated with TNF-α antagonists may develop psoriasis-like skin lesions. Clinical manifestations include palmoplantar, inverse, localized or generalized guttate, plaque-type, eczematous, and pustular lesions; deep inflammatory nodes; and nonsca…
The co-occurrence of MOG and NMDAR antibodies has been reported in a limited number of cases and is termed the overlapping syndrome (MNOS). Viral coinfections have been identified in a subset of patients with MNOS. Herein, we report the first case of M…
BackgroundRadical cystectomy remains a standard curative treatment for muscle-invasive bladder cancer (MIBC). Bladder preservation after systemic therapy without immediate surgery remains investigational and requires careful patient selection, rigorous…
BackgroundRefractory or corticosteroid-dependent juvenile generalized myasthenia gravis (gMG) remains a clinical challenge, given the scarcity of available regimens and prominent corticosteroid-related adverse effects. Telitacicept, a dual inhibitor of…
