BackgroundIsolated tricuspid valve Libman-Sacks endocarditis (LSE) is extremely rare, and its occurrence during pregnancy with severe thrombocytopenia poses major diagnostic and therapeutic challenges.Case summaryA 21-year-old pregnant woman at 13 week…
Donor cell-derived leukemia (DCL) is a rare complication of allogeneic hematopoietic cell transplantation (allo-HCT), previously described in patients receiving allo-HCT for hematologic malignancies. Allo-HCT has also been investigated as an immunother…
BackgroundHepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is characterized by intense systemic inflammation and immune dysregulation, with monocytes playing a central role in its progression. Patients with HBV-ACLF typically receive…
Eosinophilic myositis (EM) is a rare subset of idiopathic inflammatory myopathies characterized by prominent eosinophilic infiltration of skeletal muscle. It encompasses focal eosinophilic myositis (FEM), diffuse eosinophilic myositis, and eosinophilic…
We report the case of a 47-year-old woman with neuromyelitis optica spectrum disorder who developed prolonged coronavirus disease 2019 (COVID-19) pneumonia 3 months after receiving rituximab. Rituximab-induced B-cell depletion left her highly susceptib…
BackgroundThe clinical application of targeted anti-programmed cell death protein 1 (PD-1) therapy has significantly improved the prognosis of patients with various advanced malignancies. However, life-threatening immune-related adverse events remain p…
Marine seafood–derived anisakid nematodes (e.g., Anisakis spp. and Phocanema spp. [formerly Pseudoterranova spp.]) may cause gastrointestinal and allergic manifestations. Here, we report an unusual case of persistent, asymptomatic peripheral eosinophil…
Guillain-Barré syndrome (GBS) is an acute immune-mediated polyneuropathy, whereas Escherichia coli meningitis following cupping and acupuncture is a rare but severe infection. GBS as a neurological complication after E. coli meningitis is exceedingly u…
Combined central and peripheral demyelination (CCPD) is a condition characterized by concurrent demyelination in both the central and peripheral nervous systems. To date, cases of CCPD presenting with isolated optic neuritis as the initial manifestatio…
BackgroundAutoimmune encephalitis (AE) refers to a group of inflammatory brain disorders mediated by autoantibodies against neuronal surface antigens, synaptic receptors, or glial proteins. The co-occurrence of anti-N-methyl-D-aspartate receptor (NMDAR…
