BackgroundAntisynthetase syndrome (ASyS) associated with anti-EJ antibodies (directed against glycyl-tRNA synthetase) is increasingly recognized as an ILD-dominant phenotype with a propensity for rapidly progressive ILD (RP-ILD). Acute interstitial pne…
Autoimmune polyglandular syndrome type 3 (APS-3) encompasses autoimmune thyroid disease and other autoimmune disorders. APS-3B involving gastrointestinal autoimmune diseases. In this case, due to the coexistence of multiple autoimmune diseases includin…
BackgroundRenal microangiopathy is a severe complication of systemic lupus erythematosus, particularly when mediated by immune complex deposition. The optimal management of paediatric immune complex-mediated renal microangiopathy with rapid clinical de…
Introduction Leukocyte adhesion deficiency (LAD) type I is a well-recognized inborn error of immunity that typically presents in early childhood. However, cases with normal surface expression of adhesion molecules are rare and suggest that these molecu…
Disorders associated with anti-GQ1b antibodies predominantly encompass Bickerstaff brainstem encephalitis (BBE), Guillain–Barré syndrome (GBS), and Miller Fisher syndrome. Concurrent presentation of BBE, GBS, and acute transverse myelitis is exceptiona…
BackgroundImmune checkpoint inhibitors (ICIs) can cause rare but clinically important immune-related neuromuscular adverse events. Early warning signals for ICI-associated neuromuscular toxicity remain poorly defined, particularly after PD-1 inhibitor …
Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the leading cause of treatment failure in acute myeloid leukemia (AML), particularly in genetically adverse subtypes. Although prophylactic donor lymphocyte infusion (DLI) …
IntroductionUreteral wall thickening or a periureteral “sleeve” on imaging often raise concern for malignancy, but rare non-carcinomatous disorder can mimic this presentation. We report radiology and pathology findings of four prototypical cases of ure…
Immune-mediated rippling muscle disease (iRMD) is a rare autoimmune myopathy characterized by mechanically triggered, wave-like skeletal muscle contractions. Its coexistence with myasthenia gravis (MG) has been described, but detailed clinicopathologic…
FLAIR-hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES) represent a rare and distinctive clinico-radiological syndrome. Here, we report the case of a 35-year-old man who presented with sudden-onset generalized tonic-clonic…
