Jie Li ObjectiveGlioma is the most common and aggressive primary intracranial tumor. Its clinical management is substantially hindered by the blood–brain barrier (BBB) and the immunosuppressive tumor microenvironment (TME). This study aimed to construct PD-1-…
BackgroundImmune checkpoint inhibitors (ICIs) can cause rare but clinically important immune-related neuromuscular adverse events. Early warning signals for ICI-associated neuromuscular toxicity remain poorly defined, particularly after PD-1 inhibitor …
Autoimmune diseases arise from immune system dysfunction, in which immune cells erroneously attack the body’s own tissues, leading to systemic disorders or localized pathological changes. The number of patients with autoimmune diseases is gradually inc…
