BackgroundAn increased risk of severe infectious disease and acute antibody-mediated rejection (AMR) has been described after ABOi renal transplantation. We performed a prospective renal transplant study up to 5 years posttransplant to detect long-term…
ObjectiveThis study aimed to explore the value of clinical-radiomics features for predicting response to immunotherapy in extensive-stage small cell lung cancer (ES-SCLC).MethodsThis retrospective study enrolled patients with ES-SCLC who received immun…
Conventional approaches to the titration of serum antibody binding use mid-point or end-point titers that are in a relative space and are therefore difficult to standardize. Here we propose the use of the thermodynamic titer, which, under appropriate m…
BackgroundMaresin1 (MaR1), a specialized pro-resolving mediator derived from docosahexaenoic acid (DHA), exerts potent anti-inflammatory and cytoprotective actions. Its therapeutic relevance and underlying mechanisms in intestinal ischemia–reperfusion …
BackgroundSenile osteoporosis (SOP) is linked to the ubiquitination process, with dysregulation of ubiquitin-mediated protein turnover disrupting bone remodeling and resulting in decreased bone mineral density (BMD). This study aimed to identify biomar…
BackgroundChronic Obstructive Pulmonary Disease (COPD) is a progressive inflammatory lung disorder influenced by environmental and genetic factors. The rs3741240 polymorphism in the SCGB1A1 gene, which encodes the anti-inflammatory protein CC16, is con…
ObjectiveTo assess the diagnostic performance of whole-tumor histogram analysis of multiparametric MRI in predicting programmed cell death ligand-1 (PD-L1) expression in primary central nervous system lymphoma (PCNSL).MethodsA total of 130 patients wit…
IntroductionThe gut microbiome is increasingly recognized as a key modulator of immune checkpoint inhibitor (ICI) efficacy. Dietary factors, particularly fibers, may influence the microbiome and thus affect the ICI response. Although Western studies ha…
IntroductionMatrix metalloproteinases MMP-2 and MMP-9 modulate inflammatory processes at the blood–brain barrier (BBB), but their presence and function in the dura mater remain unclear. We therefore investigated their contribution to immune regulation …
ObjectiveThis study aims to identify the risk factors for central hypoventilation in patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis.MethodsPatients with anti-NMDAR encephalitis who were hospitalized between January 2020 and …
