Dendritic cells (DC) are professional antigen presenting cells playing a major role in orchestrating adaptative immune responses. To adapt to various immune challenges, such as different classes of pathogens, specialized subsets of DC have evolved acro…
IntroductionThis study aimed to investigate the prevalence of myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) in patients with optic perineuritis (OPN) and to analyze the clinical characteristics and prognosis of MOG-IgG–seropositive cases.Met…
IntroductionSepsis involves a dysregulated host response to infection and is frequently complicated by coagulopathy, contributing to organ dysfunction and mortality. Early detection of coagulation disturbances in the emergency department (ED) remains c…
BackgroundThe gut-brain axis has been increasingly recognized as a critical factor in Multiple Sclerosis (MS) pathophysiology. While its role in demyelination is well documented, gut-brain axis involvement during remyelination remains largely unexplore…
BackgroundMyocardial infarction (MI) is one of the leading causes of death worldwide. Finding reliable diagnostic biomarkers and gaining a deeper understanding of their role in the immune microenvironment is of great significance for improving clinical…
IntroductionPrurigo nodularis (PN) is a chronic inflammatory dermatosis characterized by robust pruritus and highly keratinizing nodules sympathetically distributed on the trunk and extensor sides of the limbs with an impact on quality of life and soci…
IntroductionTo identify the differences in inflammatory response between critically ill patients responding to combined bacterial-fungal sepsis and those with isolated fungal sepsis.MethodsA retrospective case-control study compared ICU patients who we…
ObjectiveThe aim of this study is to examine the relationship between hematological parameters, hemoglobin electrophoresis findings, and phenotypic characteristics in individuals carrying rare thalassemia gene variants in Northern Guangxi, China.Method…
IntroductionThis research aimed to explore key immune-related inflammatory genes and associated molecular mechanisms on hypertrophic scar (HTS), to provide new perspectives for disease prognosis and diagnosis. MethodsThe gene expression profiles were o…
BackgroundPreclinical studies have recently revealed the critical role of innate immunity in determining lung transplantation outcomes. Although the International Society for Heart and Lung Transplantation recommends high-dose corticosteroid administra…
