Nature Reviews Immunology, Published online: 02 December 2025; doi:10.1038/s41577-025-01256-0A study in Nature reports that heterotypic T cell clusters identifed in clinical samples of melanoma metastases are biologically relevant to t…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01253-3A preprint by Bockman et al. reports a cDC2-CD4+ T cell axis that mediates local tumour control after ablation of intratumoral Treg cells, wit…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01251-5A preprint by Zhijie et al. identifies somatic mutations in TYK2 that are enriched in tumour-infiltrating lymphocytes and associated with an i…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01252-4A preprint by Liu et al. shows proof-of-concept for a treatment for autoimmune diseases such as SLE using synthetic immune receptor T cells th…
Nature Reviews Immunology, Published online: 18 November 2025; doi:10.1038/s41577-025-01238-2This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomencl…
Nature Reviews Immunology, Published online: 18 November 2025; doi:10.1038/s41577-025-01246-2This poster provides an overview of the current subset-based nomenclature for T cells and a newly proposed modular nomenclature for T cells. I…
Nature Reviews Immunology, Published online: 14 November 2025; doi:10.1038/s41577-025-01245-3Short-chain fatty acids generated by the gut microbiota can support T cell ‘stemness’ and lead to improved cancer immunotherapy outcomes.
Nature Reviews Immunology, Published online: 13 November 2025; doi:10.1038/s41577-025-01237-3In this Review, the authors consider a long-standing immunological conundrum — why do neutrophils have a segmented nucleus? They discuss the m…
Nature Reviews Immunology, Published online: 11 November 2025; doi:10.1038/s41577-025-01243-5A preprint by Rivera et al. explores how retroelement expression establishes a tolerogenic environment towards food antigens in the gut, shedd…
Nature Reviews Immunology, Published online: 11 November 2025; doi:10.1038/s41577-025-01241-7A preprint by Sadiku et al. characterizes neutrophil diversity in glioblastoma using a new workflow for single-cell proteomic profiling.
