Trends in Immunology

Trends Immunol. 2026 Jun 5:S1471-4906(26)00127-4. doi: 10.1016/j.it.2026.05.002. Online ahead of print. ABSTRACT Neutrophil asthma is a severe, corticosteroid-resistant subtype characterized by airway neutrophilia and declining lung function. Su et al. identify a sirtuin 6-lactate dehydrogenase A-histone lactylation axis that links macrophage glycolysis to epigenetic chemokine regulation, offering mechanistic insight into neutrophil recruitment and highlighting potential … Read more

Trends Immunol. 2026 May 28:S1471-4906(26)00100-6. doi: 10.1016/j.it.2026.04.007. Online ahead of print. NO ABSTRACT PMID:42209365 | DOI:10.1016/j.it.2026.04.007

Trends Immunol. 2026 May 28:S1471-4906(26)00099-2. doi: 10.1016/j.it.2026.04.006. Online ahead of print. NO ABSTRACT PMID:42209364 | DOI:10.1016/j.it.2026.04.006

Trends Immunol. 2026 May 27:S1471-4906(26)00096-7. doi: 10.1016/j.it.2026.04.003. Online ahead of print. ABSTRACT Antimicrobial resistance (AMR) is one of today’s most worrisome health emergencies. Bacteria, once easily treatable with antibiotics, have acquired resistance to many or all available drugs. In 2019, 1.27 million infection-related deaths were directly caused by AMR. By 2050, AMR could put 10 … Read more

Trends Immunol. 2026 May 25:S1471-4906(26)00104-3. doi: 10.1016/j.it.2026.04.011. Online ahead of print. ABSTRACT Substance use disorders are traditionally conceptualized as disorders of brain reward circuitry; however, accumulating evidence demonstrates that addictive substances exert profound and persistent effects on central and peripheral immune and inflammatory systems. Opioids, psychostimulants, alcohol, nicotine, cannabinoids, and psychedelics modulate immune signaling across … Read more

Trends Immunol. 2026 May;47(5):339. doi: 10.1016/j.it.2026.03.012. NO ABSTRACT PMID:42167144 | DOI:10.1016/j.it.2026.03.012

Trends Immunol. 2026 May;47(5):343-344. doi: 10.1016/j.it.2026.03.014. NO ABSTRACT PMID:42167146 | DOI:10.1016/j.it.2026.03.014

Trends Immunol. 2026 May;47(5):340-342. doi: 10.1016/j.it.2026.03.013. NO ABSTRACT PMID:42167145 | DOI:10.1016/j.it.2026.03.013

Trends Immunol. 2026 May 20:S1471-4906(26)00103-1. doi: 10.1016/j.it.2026.04.010. Online ahead of print. ABSTRACT Grant writing is a career-defining skill that most researchers learn too late and without formal training. Here, we describe the integration of a structured, discipline-specific grant writing workshop into a postgraduate immunotherapy course and show that it measurably improved student confidence, funding literacy, … Read more

Trends Immunol. 2026 May 20:S1471-4906(26)00102-X. doi: 10.1016/j.it.2026.04.009. Online ahead of print. ABSTRACT Upon leaving the protective microenvironment of the primary tumor, disseminating tumor cells (DTCs) must withstand immune surveillance on their own. Cassandras et al. recently demonstrated that activation of the glucocorticoid receptor pathway serves as a critical mechanism for immune evasion during metastatic outgrowth … Read more