IntroductionEosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare necrotizing vasculitis characterized by eosinophilic inflammation that was traditionally treated with corticosteroids associated with other immunosuppressants. Over the last yea…
BackgroundAnti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis with interstitial lung disease (MDA5+ DM-ILD) carries a high mortality risk. This meta-analysis aimed to identify mortality risk factors to guide early c…
BackgroundThere is no conclusion on the effect of vitamins E and C on plasma biomarkers of oxidative stress and antioxidant status. We conducted this meta-analysis to gain a clearer view of this area.MethodsWe performed a systematic search in online da…
BackgroundIntrahepatic cholangiocarcinoma (iCC) is an aggressive hepatobiliary malignancy with limited therapeutic options and poor survival outcomes. Hepatic arterial infusion chemotherapy (HAIC) has emerged as a promising treatment alternative to sys…
ObjectiveTo comparatively evaluate the efficacy and safety of induction therapies in solid organ transplantation (SOT) using a Bayesian network meta-analysis (NMA).MethodsRandomized controlled trials (RCTs) assessing induction therapies were systematic…
BackgroundTransarterial chemoembolization (TACE) is recommended for intermediate-stage hepatocellular carcinoma (HCC). However, several therapies have shown better efficacy than TACE, meaning that the optimal therapy is unclear. We addressed this uncer…
BackgroundCurrent primary tumor treatments include curative resection, chemotherapy, and radiotherapy. However, these conventional methods lack precise drug delivery. Hydrogels, adaptable to the biological characteristics of different tumors, offer pot…
IntroductionRelapsed/refractory (r/r) large B-cell lymphoma (LBCL) remains a difficult-to-treat disease with limited treatment options and high unmet clinical need, necessitating the development of new therapies with greater potency and broader applica…
BackgroundCancer-associated fibrocytes (CAFs), a key component of the tumour microenvironment, are marked by their heterogeneity. They also exhibit a high degree of plasticity. In the last two decades there has been a strong association established bet…
BackgroundImmune-hemolytic anemia (IHA) is a rare immune-related adverse event (irAE) in cancer patients treated with immune-checkpoint inhibitors (ICIs). Although several cases of ICI-associated IHA have been reported, few attempts have been made to c…
