Pemphigoid associated with quinolone antibiotics: a real-world pharmacovigilance study of the FDA adverse event reporting system and literature-based evidence

ObjectivePemphigoid is a rare autoimmune disorder that may be drug-induced. This study aims to investigate the potential association between pemphigoid and quinolone using the FDA Adverse Event Reporting System (FAERS) database.MethodsFAERS reports wer…

The inhibitory effect of hepatic cancer energy metabolism on immune checkpoint therapy: perspectives from single-cell multi-omics analysis

ObjectiveTo investigate metabolic reprogramming—especially pyruvate metabolism—in hepatocellular carcinoma (HCC) before and after immune checkpoint inhibitor (ICI) therapy, construct a metabolism-related prognostic model, and evaluate the therapeutic p…

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