Prognostic value of longitudinal antinuclear antibody dynamics in rheumatoid arthritis: a retrospective cohort study

BackgroundThe prognostic value of longitudinal antinuclear antibody (ANA) dynamics in rheumatoid arthritis (RA) remains unclear.ObjectivesTo examine whether ANA development (titer rise/seroconversion) is associated with 12-month clinical remission and …

Lymphatic dissemination of HPV-positive oropharyngeal squamous cell carcinoma: underlying mechanisms and treatment innovations

Cancers, with its rising incidence strongly linked to human papillomavirus (HPV) infection, particularly HPV16. HPV-induced OPSCC (HPV-OPSCC) exhibits distinct biological behaviors, including a high propensity for early lymphatic metastasis, occurring …

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