BackgroundAcute Respiratory Distress Syndrome (ARDS) or its earlier stage Acute lung injury (ALI), is a worldwide health concern that jeopardizes human well-being. Currently, the treatment strategies to mitigate the incidence and mortality of ARDS are …
BackgroundBotulinum neurotoxin (BoNT) produced by Clostridium botulinum is one of the most potent known toxins. Moreover, BoNT is classified as one of the most important biological warfare agents that threatens the biosafety of the world. Currently, th…
BackgroundIn recent years, immunotherapy has been emerging as a promising alternative therapeutic method for cancer patients, offering potential benefits. The expression of PD-L1 by tumors can inhibit the T-cell response to the tumor and allow the tumo…
Mechanisms underlying long COVID remain poorly understood. Patterns of immunological responses in individuals with long COVID may provide insight into clinical phenotypes. Here we aimed to identify these immunological patterns and study the inflammator…
IntroductionThe anti-inflammatory effect of green tea extract (GTE) has been confirmed in asthmatic mice, however, the pharmacological mechanism is not fully elucidated.MethodsTo investigate the therapeutic efficacy of GTE in asthma and identify specif…
Background
Chimeric antigen receptor (CAR)-T cell quality and stemness are associated with responsiveness, durability, and memory formation, which benefit clinical responses. Autologous T cell starting material across patients with cancer is variable …
Nature Reviews Immunology, Published online: 29 April 2024; doi:10.1038/s41577-024-01027-3Here, Rongbin Zhou and colleagues review the different types of damage-associated molecular pattern (DAMP) that trigger sterile inflammation via …
Cellular & Molecular Immunology, Published online: 29 April 2024; doi:10.1038/s41423-024-01161-xTissue-specific features of innate lymphoid cells in antiviral defense
ObjectivesPrevious studies have highlighted associations between certain inflammatory cytokines and Ménière’s Disease (MD), such as interleukin (IL) -13 and IL-1β. This Mendelian randomization aims to comprehensively evaluate the causal relationships b…
