BackgroundImmune checkpoint inhibitors (ICIs) combined with chemotherapy have become an important area of clinical investigation in the gastric cancer (GC) and gastroesophageal junction cancer (GEJC). In recent years, bispecific antibody therapies have…
BackgroundNanomaterial-based therapies have emerged as a promising approach for ulcerative colitis (UC). To systematically map the field, we performed a bibliometric analysis of research over the past 25 years, aiming to reveal knowledge evolution, cor…
BackgroundRecombinant Vesicular Stomatitis Virus (rVSV) vector vaccines have become essential in combating emerging viral diseases and have shown promise in immunotherapy, particularly in the discipline of cancer treatment. Although extensive research …
BackgroundThe novel immunosuppressant belatacept demonstrates a unique mechanism of action that significantly improves renal function and reduces metabolic complications. However, systematic evidence comparing the risk of post-transplant diabetes melli…
IntroductionColorectal cancer (CRC) is one of the leading causes of morbidity and mortality worldwide. Its incidence has been strongly associated with dietary patterns of the Western diet (WD), which are characterized by high intakes of saturated fats,…
BackgroundNeuropsychiatric (NP) involvement represents one of the major challenges in Systemic Lupus Erythematosus (SLE), often requiring individualized therapeutic strategies. While anifrolumab inhibits the type I interferon receptor 1 (IFNAR1) and is…
BackgroundOsteonecrosis of the femoral head (ONFH) is a severe complication of systemic lupus erythematosus (SLE). However, the demographic characteristics, glucocorticoids (GCs) risks, and other contributing factors remain debated.ObjectiveTo elucidat…
BackgroundIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent abdominal pain or discomfort accompanied by altered bowel habits, often alongside psychological symptoms. Increasing evidence suggests that ex…
BackgroundMyasthenia gravis (MG) is a rare autoimmune disorder characterized by fluctuating muscle weakness due to impaired neuromuscular transmission. Vaccination remains a cornerstone of infectious disease prevention, yet concerns persist regarding p…
PurposeThe standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy plus esophagectomy; however, there remains a significant risk of distant metastasis following surgery, which compromises long-…
