Regulatory T cells (Tregs) are essential for immune tolerance and are under active development as cell therapy in transplantation. However, the widespread use of the calcineurin inhibitor tacrolimus may inadvertently suppress Treg proliferation and act…
This study addresses the limitations of the traditional M1/M2 binary classification for tumor-associated macrophages (TAMs) in non-small cell lung cancer (NSCLC) by introducing a NSCLC-specific functional framework based on the CXCL9/SPP1 (CS) expressi…
Generalized pustular psoriasis (GPP) in infancy is uncommon and is often precipitated by infection, drugs, or systemic inflammatory responses. Although viral illnesses such as influenza have been reported to trigger GPP, acute exacerbation secondary to…
BackgroundHuman papillomavirus (HPV) infection is strongly associated with multiple malignancies, primarily driven by the viral oncoproteins E6 and E7, which play a central role in HPV-induced malignant transformation. Although current prophylactic HPV…
BackgroundAsthma is associated with an elevated risk of venous thromboembolism and pulmonary embolism; its etiology is not completely understood.ObjectiveThis study was designed to investigate whether the formation of neutrophil extracellular traps (NE…
This study addresses the limitations of the traditional M1/M2 binary classification for tumor-associated macrophages (TAMs) in non-small cell lung cancer (NSCLC) by introducing a NSCLC-specific functional framework based on the CXCL9/SPP1 (CS) expressi…
Generalized pustular psoriasis (GPP) in infancy is uncommon and is often precipitated by infection, drugs, or systemic inflammatory responses. Although viral illnesses such as influenza have been reported to trigger GPP, acute exacerbation secondary to…
BackgroundBoth serum bile acids and inflammation have been reported to be associated with coronary artery disease (CAD). However, whether serum total bile acid (TBA) can influence the extent of atherosclerosis in premature CAD (PCAD) patients by modula…
IntroductionHidradenitis suppurativa (HS), psoriasis (PsO), and atopic dermatitis (AD) have unique disease pathogenesis and distinct pathology, despite sharing some immunological pathways. This study aimed to evaluate the transcriptomic differences bet…
PurposeSevere combined immunodeficiency (SCID) can be detected at birth through T-cell receptor excision circles (TREC) analysis in dried blood spots. This study summarizes the results of the consolidated SCID newborn screening (NBS) program in Catalon…
