Immunoglobulin A (IgA) is the most abundantly produced antibody in mammals, with its secretory dimeric form playing a central role in maintaining intestinal homeostasis. Although the J chain is known to be essential for IgA transcytosis, its precise ro…
Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues to varying degrees. They account …
Therapeutic strategies in the management of diabetic retinal diseases have typically employed anti–vascular endothelial growth factor A (anti–VEGF-A) therapies. While generally effective, clinical trials and real-world analyses demonstrate that a subst…
ObjectivesVestibular and oculomotor abnormalities have been widely identified in Fabry disease (FD), with inflammation potentially playing an important role. We aim to investigate the expression of inflammatory cytokines (ICs) in FD patients and their …
Immunoglobulin A (IgA) is the most abundantly produced antibody in mammals, with its secretory dimeric form playing a central role in maintaining intestinal homeostasis. Although the J chain is known to be essential for IgA transcytosis, its precise ro…
IntroductionAcute ischemic stroke remains a major cause of death and disability, underscoring the need for safe and effective neuroprotective strategies. Hydrogen sulfide (H₂S) exhibits dose-dependent neuroprotective effects but its therapeutic applica…
Regulatory T cells (Tregs) are essential for immune tolerance and are under active development as cell therapy in transplantation. However, the widespread use of the calcineurin inhibitor tacrolimus may inadvertently suppress Treg proliferation and act…
ObjectivesVestibular and oculomotor abnormalities have been widely identified in Fabry disease (FD), with inflammation potentially playing an important role. We aim to investigate the expression of inflammatory cytokines (ICs) in FD patients and their …
Nanotechnology plays a crucial role in vaccine development, enabling the design of functional nanoparticles (NPs) that act as both antigen carriers and adjuvants to enhance immune responses. In this study, we evaluated complex coacervate-like NPs compo…
Neurosurgical diseases—including brain tumors, hemorrhage/trauma, ischemia, infection, epilepsy, and spinal cord injury—share convergent neuro-immune mechanisms. In the acute phase, sterile inflammation and barrier disruption trigger innate immune casc…
