BackgroundApproximately 95% of ovarian teratomas are classified as benign, with only about 5% being malignant. Nevertheless, no research has previously explored the connection between primary tumor laterality and prognostic outcomes among malignant ova…
Efferocytosis is a crucial process by which apoptotic cells are removed by phagocytes such as macrophages. It not only maintains tissue homeostasis and immune tolerance, but also plays a central role in tissue repair and disease regulation. In recent y…
Endometrial cancer (EC) treatment has been revolutionized by the integration of immunotherapy, particularly for molecularly defined subsets of patients. The classification of EC into DNA polymerase epsilon-mutated (POLE-mutant), mismatch repair-deficie…
Activation of the chemokine receptor CCR6 orchestrates the trafficking of IL-17-producing pathogenic immune cells to the sites of inflammation, thus contributing to the development of numerous inflammatory and autoimmune diseases. As such, CCR6 has eme…
IntroductionLung alveolar macrophages (AMs) and epithelial cells form the first line of defense against inhaled pathogens. Their interactions strongly influence innate immune responses in the lung, yet the mechanisms underlying this cross-talk remain i…
Fibrosis is an organ dysfunction caused by excessive deposition of fibrous components produced by parenchymal cells. Effective treatments are lacking for this progressive pathological condition that manifests in various organs and can lead to mortality…
Rotaviruses are the primary cause of severe dehydrating diarrhea in infants and young children globally. Currently, several oral rotavirus vaccines are available; however, they have shown reduced effectiveness and quicker waning of protection in low- a…
IntroductionThe incidence of cancer after kidney transplantation (KT) increases owing to the use of immunosuppressive (IS) medications, which may lead to death with a functioning graft (DWFG) and reduced long-term graft survival. However, the effect of…
PurposeTo evaluate the diagnostic value of a combined strategy using the urine lipoarabinomannan (LAM) antigen assay and interferon-gamma release assay (IGRA) for active tuberculosis (TB), and to explore its potential as a non-invasive, sputum-independ…
