BackgroundDeep second-degree burns impair skin regeneration and carry high risks of scarring and infection. Achieving healing with minimal immune rejection remains challenging. Platelet-rich fibrin (PRF), an autologous biomaterial, promotes angiogenesi…
IntroductionFunctional autoantibodies targeting G protein–coupled receptors (GPCR-AAbs) have increasingly been implicated in autoimmune and inflammatory diseases. However, their relationships with established autoimmune biomarkers, such as antinuclear …
BackgroundMelanoma, a highly malignant skin tumor with high metastatic propensity and poor survival in advanced stages, poses a major global public health challenge, as conventional treatments have notable limitations. Tumor immunotherapy, particularly…
BackgroundSevere community-acquired pneumonia (SCAP) is a significant global health challenge due to its high mortality. Despite advances, early diagnosis and effective management remain critical. Tools like radiomics analyze imaging data for risk asse…
Accurate prediction of mortality after allogeneic hematopoietic stem cell transplantation (alloHCT) is essential for individualized treatment decisions, yet existing clinical risk scores capture only a limited number of variables and show modest predic…
IntroductionMacrophages participate in wound healing by contributing to host defense and by orchestrating inflammation and repair. They adapt dynamically to the wound microenvironment by adopting diverse polarization states, which are determinant of wo…
Background and objectiveType 1 diabetes (T1D) results from autoimmune destruction of pancreatic β-cells. Current therapies fail to address the multiple mechanisms driving disease progression. We developed an oral Salmonella-based vaccine that partially…
Background and objectivesProliferative lupus nephritis (LN) is a severe pathological type of systemic lupus erythematosus with a high risk of progression to chronic kidney disease and end-stage renal disease. The prognosis of patients with proliferativ…
