BackgroundWith the rising incidence of syphilis in recent decades, the number of patients with syphilis serofast has also increased, posing challenges to clinical management of patients and increasing the social burden.ObjectiveIn this study, we aimed …
Interleukin-33 (IL-33) has long been categorized as a prototypical alarmin released upon cellular injury to initiate Th2-skewed immune responses. However, accumulating evidence from diverse kidney disease models and patient cohorts has unveiled a far m…
BackgroundAutoinflammatory diseases (AIDs) are a heterogeneous group of innate immune-driven disorders whose prevalence is rising globally, yet the lack of disease-specific biomarkers continues to hamper accurate disease activity assessment, phenotype …
Recurrent chylothorax induced by thoracic duct injury in patients complicated with mixed hyperlipidemia secondary to systemic lupus erythematosus (SLE) is rarely encountered in clinical practice. A 55-year-old female patient diagnosed with SLE, whose p…
BackgroundVaccination is the most effective strategy for preventing and controlling infectious diseases in aquaculture. Edwardsiella piscicida, a Gram-negative facultative intercellular bacterial pathogen, is the etiological agent of edwardsiellosis in…
Insects are the most diverse group of animals in nature, occupying nearly every ecological niche and playing central roles as pollinators, pests, and disease vectors. Despite this vast diversity, insects rely on a set of conserved yet evolutionarily ad…
Adult human skin healing is predominantly characterized by fibrosis rather than true regeneration, despite the conserved regenerative principles observed in fetal wound healing, liver regeneration, and other biological systems. Historical and contempor…
Probiotics have gained wide popularity as environmentally sustainable replacement for antibiotics in aquaculture due to their ability to up-regulate the host immune competence and boost disease resistance. However, considerable knowledge is yet to gain…
ObjectiveResveratrol is a dietary polyphenol found in grapes, peanuts, and berries, with reported anti-inflammatory, immunomodulatory, barrier-protective, and microbiota-regulating properties. Functional dyspepsia (FD) is associated with duodenal immun…
Autoimmune diseases (ADs) are a group of inflammatory disorders triggered by aberrant immune responses against autoantigens and the breakdown of immune tolerance. Current therapeutic strategies, such as glucocorticoids and immunosuppressants, exert lar…
