Nail psoriasis (NP) is refractory in children, causing punctate pits, onycholysis, subungual hyperkeratosis and discoloration, impairing quality of life. We report a 14-year-old boy with 4-year NP, all fingernails involved with no cutaneous lesion, and…
Triple-negative breast cancer (TNBC) is an immunogenic but clinically heterogeneous breast cancer subtype. Stromal tumor-infiltrating lymphocytes (TILs), PD-L1 expression, and tumor mutational burden provide useful but incomplete summaries of the tumor…
BackgroundThe abscopal effect is a systemic anti-tumor immune response induced by local radiotherapy (RT), resulting in regression of distant, non-irradiated tumors. Although ablative RT is more effective than conventionally fractionated RT in inducing…
BackgroundThere is an increasing number of studies on the protective effects of natural products on the intestinal barrier through multiple targets. However, the landscape of knowledge structure and emerging frontiers remains incompletely characterized…
Acute kidney injury (AKI) arises from diverse insults that trigger distinct immune responses, and an integrative framework for intercellular communication is now emerging. Extracellular vesicles (EVs), membrane-enclosed particles carrying proteins, mic…
IntroductionHepatic ischemia-reperfusion injury (HIRI) is a major complication following liver transplantation (LT), contributing to graft dysfunction and rejection. The roles of the Wnt/β-catenin signaling pathway and immune responses in LT-related HI…
ObjectiveThis study aimed to integrate clinical indicators with peripheral blood T-cell subsets to develop a prediction model for ulcerative colitis (UC), and to facilitate precise subtyping and individualized treatment decisions.MethodsA retrospective…
ObjectivePulmonary nodules (PN) represent a clinically heterogeneous pathway that includes benign lesions, adenocarcinoma-spectrum lesions, and cases that may differ from clinically overt lung cancer (LC). This study aimed to define a peripheral blood …
Autoimmune encephalitis (AE) is an antibody-mediated brain disorder involving self-antibody-driven inflammation. Different subtypes present unique clinical and pathological features, influenced by variations in target antigens and underlying pathophysi…
