Correction to “Tuning the Affinity of Chimeric Antigen Receptors Enhances the Function of Human Engineered Regulatory T Cells”.
European Journal of Immunology, Volume 56, Issue 7, July 2026.
Publicaciones
Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation
Cellular & Molecular Immunology, Published online: 30 July 2026; doi:10.1038/s41423-026-01455-2Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation
Spatial metabolic heterogeneity shapes CD8+ T cell function in cancer
Curr Opin Immunol. 2026 Jul 29;102:102829. doi: 10.1016/j.coi.2026.102829. Online ahead of print. ABSTRACT Tumors are spatially heterogeneous ecosystems in which malignant, stromal, vascular, and immune cells interact within metabolically distinct niches. These localized microenvironments are shaped by factors such as nutrient availability, hypoxia, acidosis, and immunomodulatory metabolites, all of which strongly influence CD8⁺ T cell … Read more
The club cell circadian clock regulates temporal patterns in leukocyte trafficking in chronic allergic airways disease. Jafar Cain
Mucosal Immunol. 2026 Jul 29:100384. doi: 10.1016/j.mucimm.2026.100384. Online ahead of print. ABSTRACT Patients with allergic asthma exhibit distinct temporal variations in symptoms and disease severity, which oscillate across the 24 h day. We have previously shown that the molecular circadian clock plays a critical role in temporally gating the response to allergen challenge in mice. … Read more
Parental leave in immunology – 9. Marta Crespi Sallan
Trends Immunol. 2026 Jul 29:S1471-4906(26)00180-8. doi: 10.1016/j.it.2026.07.001. Online ahead of print. NO ABSTRACT PMID:42527288 | DOI:10.1016/j.it.2026.07.001
Gut dysbiosis and vitamin-dependent immune regulation in degenerative musculoskeletal and bone diseases
Degenerative musculoskeletal and metabolic bone diseases are increasingly recognized as conditions sustained not only by endocrine and mechanical factors, but also by chronic low-grade immune activation and osteo-immune imbalance. This Perspective prop…
Obesity-driven low-grade chronic inflammation as a mechanistic bridge to chronic pain: from adipose tissue remodeling to central sensitization
Obesity and chronic pain co-occur at high rates, yet the mechanistic logic that connects metabolic excess to persistent nociception remains fragmented across separate literatures. This review integrates these literatures around a single guiding questio…
LM-QASAS: reference-free identification of antigen-specific sequences from the BCR repertoire using antibody language models
The B-cell receptor (BCR) repertoire serves as a historical record of immunological events. However, deciphering antigen-specific sequences from this vast dataset remains a challenge, particularly for novel pathogens where prior knowledge is absent. Wh…
Evaluating the psychosocial and clinical impact of diagnostic delay in psoriatic arthritis: insights from a monocentric cohort
ObjectivesOur aim was to investigate the association between diagnostic delay and the clinical and psychosocial features in patients with psoriatic arthritis (PsA), with particular focus on the mental health, wellbeing, and pain-related mechanisms.Meth…